Beekeeping: find wild bees in all biomes, build beehouses to put them to work! A single beehouse won't do much, so prepare to build a few. Are you in an extreme biome? There are low-efficiency climatized beehouses available for you until you can get bees that modify allowed temperatures!
Bee breeding: Mix two breeds of bees in a beehouse, and use a brood chamber to multiply them, and an hybridization chamber to get new species (more than 30)!
Honey making: Centrifuge the combs produced by the bees to get honey and wax.
Cooking and building: honey can be used as an ingredient in cooking, and wax can be used as a building material.
Mead brewing: turn honey into mead to make your colonists happy (and drunk).
Wax lighting: candles are a quaint and cheap way to light your base
Resource gathering: many of the bees produce combs with more things than honey and wax. Will you find the Luciferium-producing bees?
Research: discover new exciting bee combinations
Pollination: plan your growing zones around your beehives and increase your crop production